Enhanced Bioactivity of Pomegranate Peel Extract following Controlled Release from CaCO₃ Nanocrystals.

ABSTRACT: Pomegranate peel extract is rich of interesting bioactive chemicals, principally phenolic compounds, which have shown antimicrobial, anticancer, and antioxidative properties. The aim of this work was to improve extract' bioactivity through the adsorption on calcium carbonate nanocrystals. Nanocrystals revealed as efficient tools for extract adsorption reaching 50% of loading efficiency. Controlled release of the contained metabolites under acidic pH has been found, as it was confirmed by quantitative assay and qualitative study through NMR analysis. Specific functionality of inorganic nanocarriers could be also tuned by biopolymeric coating. The resulting coated nanoformulations showed a great antimicrobial activity against B. cinerea fungus preventing strawberries disease better th

SUBMITTER: Baldassarre F 

PROVIDER: S-EPMC8858070 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature