Lichenysin Production by Bacillus licheniformis Food Isolates and Toxicity to Human Cells.

ABSTRACT: Bacillus licheniformis can cause foodborne intoxication due to the production of the surfactant lichenysin. The aim of this study was to measure the production of lichenysin by food isolates of B. licheniformis in LB medium and skimmed milk and its cytotoxicity for intestinal cells. Out of 11 B. licheniformis isolates tested, most showed robust growth in high salt (1M NaCl), 4% ethanol, at 37 or 55°C, and aerobic and anaerobic conditions. All strains produced lichenysin (in varying amounts), but not all strains were hemolytic. Production of this stable compound by selected strains (high producers B4094 and B4123, and type strain DSM13 ^T ) was subsequently determined using LB medium and milk, at 37 and 55°C. Lichenysin production in LB broth and milk w

SUBMITTER: Yeak KYC 

PROVIDER: S-EPMC8859269 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature