The Serious Challenge of Occult Hepatitis B Virus Infection-Related Hepatocellular Carcinoma in China.

ABSTRACT:

Background

It is unknown how many people in China have chronic occult hepatitis B virus (HBV) infection (OBI) [chronic HBV infection with negative serum hepatitis B surface antigen (HBsAg) (N-HBsAg)]. Their clinical and virological characteristics, especially the correlation between the OBI and hepatocellular carcinoma (HCC), are still elusive and need to be investigated, including prevention, early diagnosis, and treatment strategies.

Methods

138 patients with HCC related to OBI were screened from 698 patients of HCC associated with HBV infection, their characteristics of epidemiology, clinical, biochemistry, virology, diagnostics, and therapeutics were analyzed retrospectively. Furthermore, the correlation between virological features and clinical features was investigated

SUBMITTER: Xia R 

PROVIDER: S-EPMC8859271 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature