Alcohol intake and risk of glioma: results from three prospective cohort studies.

ABSTRACT:

Purpose

The association between alcohol intake and glioma remains unclear. We evaluated the association between alcohol intake and incidence of glioma in three large, prospective cohort studies with repeated alcohol assessments.

Methods

We harnessed data from three studies with repeat alcohol assessment to compute hazard ratios (HR) and 95% confidence intervals (CI) for glioma by overall alcohol intake and intake from specific beverages using Cox proportional hazards regression, adjusted for age, cohort, body mass index, smoking status, and caloric intake. Analyses were conducted separately for glioma overall and for glioblastoma (GBM).

Results

We confirmed 554 incident glioma cases (362 GBM) among 237,505 participants with 6,216,378 person-years of follow up. Cumulat

SUBMITTER: Cote DJ 

PROVIDER: S-EPMC8859697 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature