Full endoscopic versus open discectomy for sciatica: randomised controlled non-inferiority trial.

ABSTRACT:

Objective

To assess whether percutaneous transforaminal endoscopic discectomy (PTED) is non-inferior to conventional open microdiscectomy in reduction of leg pain caused by lumbar disc herniation.

Design

Multicentre randomised controlled trial with non-inferiority design.

Setting

Four hospitals in the Netherlands.

Participants

613 patients aged 18-70 years with at least six weeks of radiating leg pain caused by lumbar disc herniation. The trial included a predetermined set of 125 patients receiving PTED who were the learning curve cases performed by surgeons who did not do PTED before the trial.

Interventions

PTED (n=179) compared with open microdiscectomy (n=309).

Main outcome measures

The primary outcome was self-reported leg pain measured by a

SUBMITTER: Gadjradj PS 

PROVIDER: S-EPMC8859734 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature