Five-year follow-up study of a population-based prospective cohort of men with low-risk prostate cancer: the treatment options in prostate cancer study (TOPCS): study protocol.

ABSTRACT:

Introduction

Active surveillance (AS) is recommended for men with low-risk prostate cancer (LRPC) to reduce overtreatment and to maintain patients' quality of life (QOL). However, whether African American (AA) men can safely undergo AS is controversial due to concerns of more aggressive disease and lack of empirical data on the safety and effectiveness of AS in this population. Withholding of AS may lead to a lost opportunity for improving survivorship in AA men. In this study, peer-reviewed and funded by the US Department of Defense, we will assess whether AS is an equally effective and safe management option for AA as it is for White men with LRPC.

Methods and analysis

The project extends follow-up of a large contemporary population-based cohort of LRPC patients (n=1688) w

SUBMITTER: Xu J 

PROVIDER: S-EPMC8860062 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature