Nonstudent Young Men Put Students at High Risk of HIV Acquisition in Guangxi, China: A Phylogenetic Analysis of Surveillance Data.

ABSTRACT:

Background

We sought to identify students and their sexual partners in a molecular transmission network.

Methods

We obtained 5996 HIV protease and reverse transcriptase gene sequences in Guangxi (165 from students and 5831 from the general populations) and the relevant demographic data. We constructed a molecular transmission network and introduced a permutation test to assess the robust genetic linkages. We calculated the centrality measures to describe the transmission patterns in clusters.

Results

At the network level, 68 (41.2%) students fell within the network across 43 (8.1%) clusters. Of 141 genetic linkages between students and their partners, only 25 (17.7%) occurred within students. Students were more likely than random permutations to link to other students

SUBMITTER: Jiang H 

PROVIDER: S-EPMC8860155 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature