Variables Associated With Response to Therapy in Patients With Interstitial Pneumonia With Autoimmune Features.

ABSTRACT:

Background/objective

We have limited knowledge regarding characteristics of patients with interstitial pneumonia with autoimmune features (IPAF) that are associated with response to immunosuppression. In this study, we used published IPAF criteria to characterize features associated with response to treatment.

Methods

We conducted a single-center medical records review study of 63 IPAF patients to evaluate for serological, clinical, and morphological characteristics that are associated with response to immunosuppression. Response was defined as % relative functional vital capacity decline of less than 10% and absence of death or lung transplant within the first year of continuous immunosuppressive therapy. Nonparametric measures of association and multivariate logistic regre

SUBMITTER: Joerns EK 

PROVIDER: S-EPMC8860209 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature