A radiomics model can distinguish solitary pulmonary capillary haemangioma from lung adenocarcinoma.

ABSTRACT:

Objectives

Solitary pulmonary capillary haemangioma (SPCH) is a benign lung tumour that presents as ground-glass nodules on computed tomography (CT) images and mimics lepidic-predominant adenocarcinoma. This study aimed to establish a discriminant model using a radiomic feature analysis to distinguish SPCH from lepidic-predominant adenocarcinoma.

Methods

In the adenocarcinoma group, all tumours were of the lepidic-predominant subtype with high purity (>70%). A classification model was proposed based on a two-level decision tree and 26 radiomic features extracted from each segmented lesion. For comparison, a baseline model was built with the same 26 features using a support vector machine as the classifier. Both models were assessed by the leave-one-out cross-validation metho

SUBMITTER: Wang HJ 

PROVIDER: S-EPMC8860424 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature