Cardiac troponins predict mortality and cardiovascular outcomes in patients with peripheral artery disease: A systematic review and meta-analysis of adjusted observational studies.

ABSTRACT:

Background

A significant proportion of patients (pts) with peripheral artery disease (PAD) have concomitant coronary artery disease and polyvascular involvement contributes to increased risk of death and unfavorable cardiovascular events.

Hypothesis

Cardiac troponins are associated with adverse cardiovascular outcomes in PAD pts.

Methods

We systematically searched Medline and Scopus to identify all observational cohort studies published before June 2021 (combining terms "troponin," "peripheral artery disease," "peripheral arterial disease," "intermittent claudication," and "critical limb ischemia") that evaluated the prognostic impact of troponin rise on admission on all-cause mortality and/or major cardiovascular events (MACEs; composite of myocardial infarction, str

SUBMITTER: Vrsalovic M 

PROVIDER: S-EPMC8860477 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature