Comparative effects of left bundle branch area pacing, His bundle pacing, biventricular pacing in patients requiring cardiac resynchronization therapy: A network meta-analysis.

ABSTRACT:

Background

The comparative effects of different types of cardiac resynchronization therapy (CRT) delivered by biventricular pacing (BVP), His bundle pacing (HBP), and left bundle branch area pacing (LBBAP) remain inconclusive.

Hypothesis

HBP and LBBAP may be advantageous over BVP for CRT.

Methods

PubMed, Embase, Web of Science, and the Cochrane Library were systematically searched for studies that reported the effects after BVP, HBP, and LBBAP for CRT. The effects between groups were compared by a frequentist random-effects network meta-analysis (NMA), by which the mean differences (MDs) and 95% confidence intervals (CIs) were calculated.

Results

Six articles involving 389 patients remained for the final meta-analysis. The mean follow-up of these studies was 8.

SUBMITTER: Hua J 

PROVIDER: S-EPMC8860481 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature