Intratympanic corticosteroid as salvage therapy in treatment of idiopathic sudden sensorineural hearing loss: A systematic review and meta-analysis.

ABSTRACT:

Background

The standard treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) constitutes of systemic oral corticosteroid. Although oral corticosteroid might revert the acute deafness, some patients with ISSNHL display a more treatment refractory course. For these patients, corticosteroid installed directly into the middle ear has become a more frequent treatment, due to the potential benefits of a high, local concentration compared to a systemic administration. As such, for patients being refractory to standard treatment, intratympanic injection of a high dosage of corticosteroid as salvage therapy may be beneficial.

Objectives

To evaluate the efficacy of intratympanic corticosteroid (ITC) as a salvage treatment of ISSNHL.

Methods

A systematic literature

SUBMITTER: Devantier L 

PROVIDER: S-EPMC8860923 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature