Effect of MIND diet intervention on cognitive performance and brain structure in healthy obese women: a randomized controlled trial.

ABSTRACT: Previous studies suggested adherence to recently developed Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) associated with cognitive performance. This study aimed to examine the effect of MIND dietary pattern on cognitive performance features and changes in brain structure in healthy obese women. As a total of 50 obese women were assessed for eligibility, we randomly allocated 40 participants with mean BMI 32 ± 4.31 kg/m² and mean age 48 ± 5.38 years to either calorie-restricted modified MIND diet or a calorie-restricted standard control diet. Change in cognitive performance was the primary outcome measured with a comprehensive neuropsychological test battery. We also performed voxel-based morphometry as a secondary outcome to quantify the differences in brain

SUBMITTER: Arjmand G 

PROVIDER: S-EPMC8861002 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature