How low working memory demands and reduced anticipatory attentional gating contribute to impaired inhibition during acute alcohol intoxication.

ABSTRACT: High-dose alcohol intoxication is commonly associated with impaired inhibition, but the boundary conditions, as well as associated neurocognitive/neuroanatomical changes have remained rather unclear. This study was motivated by the counterintuitive finding that high-dose alcohol intoxication compromises response inhibition performance when working memory demands were low, but not when they were high. To investigate whether this is more likely to be caused by deficits in cognitive control processes or in attentional processes, we examined event-related (de)synchronization processes in theta and alpha-band activity and performed beamforming analyses on the EEG data of previously published behavioral findings. This yielded two possible explanations: There may be a selective decrease of workin

SUBMITTER: Stock AK 

PROVIDER: S-EPMC8861183 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature