Pyroptosis-Related Signatures for Predicting Prognosis in Breast Cancer.

ABSTRACT:

Background

Female breast cancer (BC) has become the most common cancer in the world, and its mortality was considerably higher in transitioning vs. transitioned countries. Pyroptosis, an inflammation-dependent programmed cell death mediated by inflammasomes, has been observed in human colorectal tumors and gliomas. However, the characteristics of pyrolysis-related genes and their influence and mechanism on the tumorigenesis and progress of BC were unknown.

Methods

Based on the global public database, we used comprehensive bioinformatics analysis to systematically analyze the expression of pyroptosis-related genes in BC and their relationship in tumor progression. In addition, BC patients were divided into two groups, and the clinical features and outcomes could be better pre

SUBMITTER: Ren T 

PROVIDER: S-EPMC8861281 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature