Virulence Biomarkers of Bursaphelenchus xylophilus: A Proteomic Approach.

ABSTRACT: The pinewood nematode (PWN), Bursaphelenchus xylophilus, one of the most serious forest pests worldwide, is considered the causal agent of the pine wilt disease (PWD). The main host species belong to the genus Pinus, and a variation in the susceptibility of several pine species to PWN infection is well-known. It is also recognized that there is variation in the virulence among B. xylophilus isolates. In the present study, we applied a quantitative mass spectrometry-based proteomics approach to perform a deep characterization of proteomic changes across two B. xylophilus isolates with different virulence from different hosts and geographical origins. A total of 1,456 proteins were quantified and compared in the two isolates secretomes, and a total of 2,741 protei

SUBMITTER: Cardoso JMS 

PROVIDER: S-EPMC8861294 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature