Methylphenidate Use and Infectious Diseases in Children With Attention Deficit and Hyperactivity Disorder: A Population-Based Study.

ABSTRACT:

Objective

Children with attention deficit hyperactivity disorder (ADHD) have more visits to the emergency department (ED) due to injuries than those without ADHD. However, no study has investigated whether children with ADHD have more ED visits or hospitalizations due to infectious diseases (IDs) and whether methylphenidate (MPH) treatment may reduce the risk.

Method

The incidence of ID-related ED visits or hospitalizations was defined as the main outcome. The Cox regression and conditional Poisson regression models were calculated to estimate hazard ratios (HRs) in the population level and relative risks for the self-controlled case series design, respectively.

Results

Children with ADHD had higher rates of emergency visits (HR = 1.25, 95% CI: 1.

SUBMITTER: Chen VC 

PROVIDER: S-EPMC8861374 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature