Does COVID-19 increase the long-term relapsing-remitting multiple sclerosis clinical activity? A cohort study.

ABSTRACT:

Background

Some current evidence is pointing towards an association between COVID-19 and worsening of multiple sclerosis (MS), stressing the importance of preventing COVID-19 among people with MS (pwMS). However, population-based evidence regarding the long-term post-COVID-19 course of relapsing-remitting multiple sclerosis (RRMS) was limited when this study was initiated.

Objective

To detect possible changes in MS clinical disease activity after COVID-19.

Methods

We conducted an observational study from July 2020 until July 2021 in the Isfahan MS clinic, comparing the trends of probable disability progression (PDP) - defined as a three-month sustained increase in expanded disability status scale (EDSS) score - and relapses before and after probable/definitive COVID-1

SUBMITTER: Etemadifar M 

PROVIDER: S-EPMC8861623 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature