Risk Factors and Prognosis of Early Posttraumatic Seizures in Moderate to Severe Traumatic Brain Injury.

ABSTRACT:

Importance

Early posttraumatic seizures (EPS) that may occur following a traumatic brain injury (TBI) are associated with poorer outcomes and development of posttraumatic epilepsy (PTE).

Objective

To evaluate risk factors for EPS, associated morbidity and mortality, and contribution to PTE.

Design, setting, and participants

Data were collected from an Australian registry-based cohort study of adults (age ≥18 years) with moderate to severe TBI from January 2005 to December 2019, with 2-year follow-up. The statewide trauma registry, conducted on an opt-out basis in Victoria (population 6.5 million), had 15 152 patients with moderate to severe TBI identified via Abbreviated Injury Scale (AIS) head severity score, with an opt-out rate less than 0.5% (opt-out n = 136).

SUBMITTER: Laing J 

PROVIDER: S-EPMC8861899 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature