Risk of Second Allergic Reaction to SARS-CoV-2 Vaccines: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Vaccination against SARS-CoV-2 is a highly effective strategy to prevent infection and severe COVID-19 outcomes. The best strategy for a second dose of vaccine among persons who had an immediate allergic reaction to their first SARS CoV-2 vaccination is unclear.

Objective

To assess the risk of severe immediate allergic reactions (eg, anaphylaxis) to a second dose of SARS-CoV-2 mRNA vaccine among persons with immediate allergic reactions to their first vaccine dose.

Data sources

MEDLINE, Embase, Web of Science, and the World Health Organization Global Coronavirus database were searched from inception through October 4, 2021.

Study selection

Included studies addressed immediate allergic reactions of any severity to a second SARS-CoV-2 vaccine dose in p

SUBMITTER: Chu DK 

PROVIDER: S-EPMC8861900 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature