Heart rate variability is associated with left ventricular systolic, diastolic function and incident heart failure in the general population.

ABSTRACT:

Background

HRV has mostly shown associations with systolic dysfunction and more recently, with diastolic dysfunction in Heart failure (HF) patients. But the role of sympathetic nervous system in changes of left ventricular (LV) systolic and diastolic function and new-onset HF has not been extensively studied.

Methods

Among 3157 men and 4405 women free of HF and atrial fibrillation retrospectively included from the population-based Rotterdam Study, we used linear mixed models to examine associations of RR-interval differences and standard deviation of RR-intervals corrected for heart rate (RMSSDc and SDNNc) with longitudinal changes of LV ejection fraction (LVEF), E/A ratio, left atrial (LA) diameter, E/e' ratio. Afterwards, using cox regressions, we examined their associatio

SUBMITTER: Arshi B 

PROVIDER: S-EPMC8862241 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature