Sex-based differences in left ventricular remodeling in patients with chronic aortic regurgitation: a multi-modality study.

ABSTRACT:

Background

Significant aortic regurgitation (AR) leads to left ventricular (LV) remodeling; however, little data exist regarding sex-based differences in LV remodeling in this setting. We sought to compare LV remodeling and AR severity, assessed by echocardiography and cardiovascular magnetic resonance (CMR), to discern sex-based differences.

Methods

Patients with ≥ moderate chronic AR by echocardiography who underwent CMR within 90 days between December 2005 and October 2015 were included. Nonlinear regression models were built to assess the effect of AR regurgitant fraction (RF) on LV remodeling. A generalized linear model and Bland Altman analyses were constructed to evaluate differences between CMR and echocardiography. Referral for surgical intervention based on symptom

SUBMITTER: Tower-Rader A 

PROVIDER: S-EPMC8862390 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature