Multiple sclerosis and inflammatory bowel disease: A systematic review and meta-analysis.

ABSTRACT:

Background

Multiple sclerosis (MS) and inflammatory bowel disease (IBD) are two autoimmune diseases that seriously affect patients' quality of life. Previous studies have established an association between MS and IBD, including Crohn's disease (CD) and ulcerative colitis (UC), but the results were inconsistent. The aim of this study was to quantify the prevalences of and the association between MS and IBD.

Methods

The PubMed, Web of Science, and Embase databases were searched through November 2020 for studies reporting data on MS among patients with IBD and vice versa. The main outcomes were the proportion of MS in patients with IBD and vice versa, as well as the association (risk ratio [RR]) of IBD in MS and that of MS in IBD.

Results

Based on the analysis of 17 stud

SUBMITTER: Wang X 

PROVIDER: S-EPMC8862424 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature