Estimating the effect of practicing nursing professionals density on cumulative carbapenem-resistance prevalence in gram-negative invasive Isolates: a 30 European country observational modeling study.

ABSTRACT:

Background

The burden of antimicrobial-resistance, specifically carbapenem-resistance in gram-negative bacteria (CRGN), presents a serious public health threat worldwide. In Europe, Southern and Eastern countries (SEC) display a higher CRGN-prevalence as compared to Northern and Western countries (NWC). Since SEC also display lower nurse-density on average, we hypothesized that the occurrence of CRGN might correlate with nurse understaffing and therefore aimed at quantifying a potential independent effect of nurse-density on total CRGN in Europe.

Methods

A 30-country cross-sectional study was conducted. Cumulative six-year CRGN-prevalence (2011-2016) in four gram-negative bacterial species was determined based on > 700 k clinical invasive isolates (EARS-net). We performed mu

SUBMITTER: Kaba HEJ 

PROVIDER: S-EPMC8862581 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature