Genomic Analysis of Community Transmission Networks for MRSA Among Females Entering a Large Inner-city Jail.

ABSTRACT:

Background

It is unclear if there are differences in methicillin-resistant Staphylococcus aureus (MRSA) risk between sexes in high-risk populations.

Methods

Females incarcerated at the Cook County Jail were enrolled within 72 hours of intake. Surveillance cultures (nares, throat, groin) were collected to determine the prevalence of MRSA colonization. A survey was administered to identify colonization predictors. Univariate and multivariate analyses were performed to identify predictors of colonization at intake. Genomic sequencing was performed on MRSA colonization and archived clinical isolates.

Results

Two hundred fifty women were enrolled (70% African American, 15% Hispanic), with 70% previously in jail. The prevalence of MRSA colonization at intake was 20%,

SUBMITTER: Popovich KJ 

PROVIDER: S-EPMC8863081 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature