The public health impact of poor sleep on severe COVID-19, influenza and upper respiratory infections.

ABSTRACT:

Background

Poor sleep is associated with an increased risk of infections and all-cause mortality, and acute sleep loss and disruption have been linked with inflammation and poorer immune control. Previous studies, however, have been unable to evidence causality between the chronic effects of poor sleep and respiratory infection risk. In light of the ongoing COVID-19 pandemic and potential future disease outbreaks, understanding the risk factors for these infections is of great importance.

Aim

Our goal was to understand if chronic poor sleep could be identified as a causal risk factor for respiratory infections including influenza, upper respiratory infections and COVID-19.

Methods

We used population cohorts from the UK Biobank (N ≈ 231,000) and FinnGen (N ≈ 327,000) w

SUBMITTER: Jones SE 

PROVIDER: S-EPMC8863167 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature