Repeat Measures of Lipoprotein(a) Molar Concentration and Cardiovascular Risk.

ABSTRACT:

Background

When indicated, guidelines recommend measurement of lipoprotein(a) for cardiovascular risk assessment. However, temporal variability in lipoprotein(a) is not well understood, and it is unclear if repeat testing may help refine risk prediction of coronary artery disease (CAD).

Objectives

The authors examined the stability of repeat lipoprotein(a) measurements and the association between instability in lipoprotein(a) molar concentration with incident CAD.

Methods

The authors assessed the correlation between baseline and first follow-up measurements of lipoprotein(a) in the UK Biobank (n = 16,017 unrelated individuals). The association between change in lipoprotein(a) molar concentration and incident CAD was assessed among 15,432 participants using Cox proport

SUBMITTER: Trinder M 

PROVIDER: S-EPMC8863206 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature