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Acceptability of an extended duration vaginal ring for HIV prevention and interest in a multi-purpose ring.


ABSTRACT: Given challenges with adherence to existing HIV prevention products, the development of an extended duration vaginal ring could improve adherence while reducing patient and provider burden. Additionally, women have other interlinked sexual health concerns such as unintended pregnancy. We evaluated acceptability of a 90-day ring to prevent HIV and hypothetical preferences for a dual (HIV and contraceptive) indication. This was a secondary analysis of a Phase 1, two-arm, multi-site, placebo-controlled randomized trial evaluating safety and pharmacokinetics of a 90-day vaginal ring containing tenofovir for HIV prevention (N = 49). We used a mixed methods approach to assess quantitative data on acceptability (n = 49) and used qualitative data from a random subset to explain the quantitative fi

SUBMITTER: Stoner MCD 

PROVIDER: S-EPMC8863232 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature