Imaging visuospatial memory in temporal lobe epilepsy-Results of an fMRI study.

ABSTRACT:

Purpose

Impairment of cognitive functions is commonly observed in temporal lobe epilepsy (TLE). The aim of this study was to assess visuospatial memory functions and memory-related networks using an adapted version of Roland's Hometown Walking (RHWT) functional MRI (fMRI) task in patients with TLE.

Methods

We used fMRI to study activation patterns based on a visuospatial memory paradigm in 32 TLE patients (9 right; 23 left) and also within subgroups of lesional and non-lesional TLE. To test for performance, a correlational analysis of fMRI activation patterns and out-of-scanner neuropsychological visuospatial memory testing was performed. Additionally, we assessed memory-related networks using functional connectivity (FC).

Results

Greater contralateral than ipsilatera

SUBMITTER: Schmidbauer V 

PROVIDER: S-EPMC8863287 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature