The Association among Blood Pressure, Blood Pressure Medications, and Glaucoma in a Nationwide Electronic Health Records Database.

ABSTRACT:

Purpose

To measure the association among blood pressure (BP), BP medications, and glaucoma using the All of Us Research Program database.

Design

A retrospective, longitudinal cohort study leveraging a national electronic health record (EHR) database administered by the National Institutes of Health.

Participants

Eye patients in the All of Us Research Program database with at least 15 months of follow-up and 1 BP measurement.

Methods

Univariable and multivariable Cox regression models predicted the risk of developing incident open-angle glaucoma (OAG). Mean arterial pressure (MAP) and the number of BP medication classes were entered as time-varying predictors to account for changes over time.

Main outcome measures

The risk of developing incident OAG, as d

SUBMITTER: Lee EB 

PROVIDER: S-EPMC8863625 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature