Dataset Information

Bayesian-based decipherment of in-depth information in bacterial chemical sensing beyond pleasant/unpleasant responses.

ABSTRACT: Chemical sensing is vital to the survival of all organisms. Bacterial chemotaxis is conducted by multiple receptors that sense chemicals to regulate a single signalling system controlling the transition between the direction (clockwise vs. counterclockwise) of flagellar rotation. Such an integrated system seems better suited to judge chemicals as either favourable or unfavourable, but not for identification purposes though differences in their affinities to the receptors may cause difference in response strength. Here, an experimental setup was developed to monitor behaviours of multiple cells stimulated simultaneously as well as a statistical framework based on Bayesian inferences. Although responses of individual cells varied substantially, ensemble averaging of the time courses seemed characteristic to attractant species, indicating we can extract information of input chemical species from responses of the bacterium. Furthermore, two similar, but distinct, beverages elicited attractant responses of cells with profiles distinguishable with the Bayesian procedure. These results provide a basis for novel bio-inspired sensors that could be used with other cell types to sense wider ranges of chemicals.

SUBMITTER: Tanaka H

PROVIDER: S-EPMC8863824 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

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Publications

Bayesian-based decipherment of in-depth information in bacterial chemical sensing beyond pleasant/unpleasant responses.

Tanaka Hiroto H Kazuta Yasuaki Y Naruse Yasushi Y Tominari Yukihiro Y Umehara Hiroaki H Sowa Yoshiyuki Y Sagawa Takashi T Oiwa Kazuhiro K Okada Masato M Kawagishi Ikuro I Kojima Hiroaki H

Scientific reports 20220222 1

Chemical sensing is vital to the survival of all organisms. Bacterial chemotaxis is conducted by multiple receptors that sense chemicals to regulate a single signalling system controlling the transition between the direction (clockwise vs. counterclockwise) of flagellar rotation. Such an integrated system seems better suited to judge chemicals as either favourable or unfavourable, but not for identification purposes though differences in their affinities to the receptors may cause difference in ...[more]

PMID: 35194068

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Project description:The evaluation of building facades is one of the most important elements in built environments for helping architects and professionals to develop future designs. The form or shape of windows in building facades has direct impacts on perceivers' affective state and emotions. To understand the impacts of geometric windows on the subject's feedback and cortical activity, psychophysics experiments and electroencephalogram (EEG) recordings were measured from the participants. Our behavioral results show a distinguished categorization of the window shapes as pleasant and unpleasant stimuli. The rectangular, square, circular and semi-circular arch were determined as the pleasant window shapes, while the triangular and triangular arch window shapes were distinguished as unpleasant. Furthermore, event-related potential (ERP) components (N1, P2 and P3) were investigated to determine the influence of window shapes on the local brain activity. To measure reliable cortical responses, a Butterworth notch filter (50 Hz), band pass filter (0.1-60 Hz) and ADJUST filter were employed to remove the artifacts. The electrophysiological results show increased activity for the unpleasant in comparison to the pleasant windows (p < 0.05, Rank-Sum test) in both frontal (for P2 component) and posterio-occipital (ERP amplitudes; the N1 through to the P3 peak) channels. The ERP amplitudes of the right hemisphere were significantly larger than in the left hemisphere, not only in response to the unpleasant (p < 0.001) but also to the pleasant window stimuli (p < 0.001, Signed-Rank test). However, the unpleasant stimuli evoked significantly larger ERP amplitude than the pleasant stimuli. Moreover, the significant ERPP2 amplitude was more distinguished for unpleasant (p = 0.01, Signed-Rank test) than pleasant windows (p = 0.01, Rank-Sum test) between frontal and central cortical lobes. Overall, our behavioral and electrophysiological studies demonstrate a distinguished categorization of pleasant and unpleasant window shapes and more significant ERP modulations in the right than left hemisphere for unpleasant windows compared to pleasant ones.

Dataset Information

Bayesian-based decipherment of in-depth information in bacterial chemical sensing beyond pleasant/unpleasant responses.

Publications

Bayesian-based decipherment of in-depth information in bacterial chemical sensing beyond pleasant/unpleasant responses.

Similar Datasets

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