The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication.

ABSTRACT: The coronavirus disease 2019 (COVID-19) is a highly transmissible disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that poses a major threat to global public health. Although COVID-19 primarily affects the respiratory system, causing severe pneumonia and acute respiratory distress syndrome in severe cases, it can also result in multiple extrapulmonary complications. The pathogenesis of extrapulmonary damage in patients with COVID-19 is probably multifactorial, involving both the direct effects of SARS-CoV-2 and the indirect mechanisms associated with the host inflammatory response. Recognition of features and pathogenesis of extrapulmonary complications has clinical implications for identifying disease progression and designing therapeutic strategies. This

SUBMITTER: Ning Q 

PROVIDER: S-EPMC8863906 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature