Predicting ionized hypocalcemia: External validation of an ionized calcium prediction model in patients with COVID-19 and renal failure.

ABSTRACT:

Background

Ionized hypocalcemia is common in critically ill patients with COVID-19 and is associated with adverse outcomes. We previously developed a linear model that estimates ionized calcium (I_Ca) by adjusting total calcium (T_Ca) for the three components of the anion gap and albumin. On internal validation, it outperformed the popular method that corrects T_Ca for albumin alone (cT_Ca) in diagnosing low I_Ca. In this study, we sought to externally validate our I_Ca model in hospitalized COVID-19 positive patients.

Methods

We retrospectively studied all 200 patients with COVID-19 who were admitted to the State University of New York Downstate Medical Center between March 11^th and April 30^th

SUBMITTER: Yap E 

PROVIDER: S-EPMC8864233 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature