SARS-CoV-2 antigen lateral flow tests for detecting infectious people: linked data analysis.

ABSTRACT:

Objectives

To investigate the proportion of lateral flow tests (LFTs) that produce negative results in those with a high risk of infectiousness from SARS-CoV-2, to investigate the impact of the stage and severity of disease, and to compare predictions made by influential mathematical models with findings of empirical studies.

Design

Linked data analysis combining empirical evidence of the accuracy of the Innova LFT, the probability of positive viral culture or transmission to secondary cases, and the distribution of viral loads of SARS-CoV-2 in individuals in different settings.

Setting

Testing of individuals with symptoms attending NHS Test-and-Trace centres across the UK, residents without symptoms attending municipal mass testing centres in Liverpool, and students

SUBMITTER: Deeks JJ 

PROVIDER: S-EPMC8864475 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature