Randomized trial of cognitive training and brain stimulation in non-demented older adults.

ABSTRACT:

Introduction

Given rapid global population aging, developing interventions against age-associated cognitive decline is an important medical and societal goal. We evaluated a cognitive training protocol combined with transcranial direct current stimulation (tDCS) on trained and non-trained functions in non-demented older adults.

Methods

Fifty-six older adults (65-80 years) were randomly assigned to one of two interventional groups, using age and baseline performance as strata. Both groups performed a nine-session cognitive training over 3 weeks with either concurrent anodal tDCS (atDCS, 1 mA, 20 minutes) over the left dorsolateral prefrontal cortex (target intervention) or sham stimulation (control intervention). Primary outcome was performance on the trained letter updating

SUBMITTER: Antonenko D 

PROVIDER: S-EPMC8864498 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature