Associations between aflatoxin B₁-albumin adduct levels with metabolic conditions in Guatemala: A cross-sectional study.

ABSTRACT:

Background and aims

Metabolic conditions such as obesity, type 2 diabetes, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD) are highly prevalent in Guatemala and increase the risk for a number of disorders, including hepatocellular carcinoma (HCC). Aflatoxin B₁ (AFB₁) levels are also notably elevated in the population and are known to be associated with HCC risk. Whether AFB₁ also contributes to the high prevalence of the metabolic disorders has not been previously examined. Therefore, the purpose of this study was to assess the association between AFB₁ and the metabolic conditions.

Methods

Four-hundred twenty-three individuals were included in the study, in which AFB₁-albumin adduct levels were measured

SUBMITTER: Alvarez CS 

PROVIDER: S-EPMC8865065 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature