Factors affecting postural instability after more than one-year bilateral subthalamic stimulation in Parkinson's disease: A cross-sectional study.

ABSTRACT:

Background

Balance impairment in Parkinson's disease is multifactorial and its changes due to subthalamic stimulation vary in different studies.

Objective

We aimed to analyze the combination of predictive clinical factors of balance impairment in patients with Parkinson's disease treated with bilateral subthalamic stimulation for at least one year.

Methods

We recruited 24 patients with Parkinson's disease treated with bilateral subthalamic stimulation and 24 healthy controls. They wore an Opal monitor (APDM Inc.) consisting of three-dimensional gyroscopes and accelerometers in the lumbar region. We investigated four stimulation conditions (bilateral stimulation OFF, bilateral stimulation ON, and unilateral right- and left-sided stimulation ON) with four tests: stance

SUBMITTER: Kelemen A 

PROVIDER: S-EPMC8865658 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature