Impact of Low Rates of Influenza on Next-Season Influenza Infections.

ABSTRACT:

Introduction

Interventions to curb the spread of COVID-19 during the 2020-2021 influenza season essentially eliminated influenza during that season. Given waning antibody titers over time, future residual population immunity against influenza will be reduced. The implication for the subsequent 2021-2022 influenza season is unknown.

Methods

An agent-based model of influenza implemented in the Framework for Reconstructing Epidemiological Dynamics simulation platform was used to estimate cases and hospitalizations over 2 successive influenza seasons. The impact of reduced residual immunity owing to protective measures in the first season was estimated over varying levels of similarity (cross-immunity) between influenza strains over the seasons.

Results

When cross-immunit

SUBMITTER: Krauland MG 

PROVIDER: S-EPMC8866158 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature