Sex-specific developmental trajectories of eczema from infancy to age 26 years: A birth cohort study.

ABSTRACT:

Background

Eczema is a common inflammatory skin disease with varying developmental trajectories/patterns that are influenced by different risk factors. The aim of this study was to investigate eczema development from infancy to early adulthood by identifying distinct developmental trajectories that describe disease patterns over time and evaluate the role of prenatal and early-life risk factors.

Methods

The Isle of Wight Birth Cohort (n = 1456) was prospectively assessed at birth, 1, 2, 4, 10, 18 and 26 years. In all assessments, eczema was defined as chronic or chronically relapsing itchy dermatitis lasting >6 weeks with characteristic morphology and distribution in the past 12 months. Developmental trajectories of eczema between 1 or 2 and 26 years were identified separate

SUBMITTER: Ziyab AH 

PROVIDER: S-EPMC8866217 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature