Survival Genie, a web platform for survival analysis across pediatric and adult cancers.

ABSTRACT: The genomics data-driven identification of gene signatures and pathways has been routinely explored for predicting cancer survival and making decisions related to targeted treatments. A large number of packages and tools have been developed to correlate gene expression/mutations to the clinical outcome but lack the ability to perform such analysis based on pathways, gene sets, and gene ratios. Furthermore, in this single-cell omics era, the cluster markers from cancer single-cell transcriptomics studies remain an underutilized prognostic option. Additionally, no bioinformatics online tool evaluates the associations between the enrichment of canonical cell types and survival across cancers. Here we have developed Survival Genie, a web tool to perform survival analysis on single-cell RNA-seq

SUBMITTER: Dwivedi B 

PROVIDER: S-EPMC8866543 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature