Analysis and quantification of female and male contributions to the first stages of embryonic kinetics: study from a time-lapse system.

ABSTRACT:

Purpose

The few studies that examined the effect of male and/or female features on early embryo development, notably using the time-lapse system (TL), reported conflicting results. This can be explained by the small number of studies using an adapted model.

Methods

We used two original designs to study the female and male effects on embryo development: (1) based on embryos from donor oocytes (TL-DO), and (2) from donor sperm (TL-DS). Firstly, we analyzed the female and male similarities using an ad hoc intraclass correlation coefficient (ICC), then we completed the analysis with a multivariable model to assess the association between both male and female factors, and early embryo kinetics. A total of 572 mature oocytes (TL-DO: 293; TL-DS: 279), fertilized by intracytoplasmic

SUBMITTER: Bruno C 

PROVIDER: S-EPMC8866590 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature