Magnetophoretic Micro-Distributor for Controlled Clustering of Cells.

ABSTRACT: Cell clustering techniques are important to produce artificial cell clusters for in vitro models of intercellular mechanisms at the single-cell level. The analyses considering physical variables such as the shape and size of cells have been very limited. In addition, the precise manipulation of cells and control of the physical variables are still challenging. In this paper, a magnetophoretic device consisting of a trampoline micromagnet and active elements that enable the control of individual selective jumping motion and positioning of a micro-object is proposed. Based on a numerical simulation under various conditions, automatic separation or selective clustering of micro-objects according to their sizes is performed by parallel control and programmable manipulation. This method provide

SUBMITTER: Yoon J 

PROVIDER: S-EPMC8867205 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature