Ontology highlight
ABSTRACT:
SUBMITTER: Cabral de Guimaraes TA
PROVIDER: S-EPMC8867261 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Cabral de Guimaraes Thales Antonio TA Daich Varela Malena M Georgiou Michalis M Michaelides Michel M
The British journal of ophthalmology 20210319 3
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the developed world. The identification of the central role of vascular endothelial growth factor (VEGF) in the pathogenesis of neovascular AMD and the introduction of anti-VEGF agents as gold-standard treatment, have drastically changed its prognosis-something yet to be seen in dry AMD. Several therapeutic avenues with a wide variability of targets are currently being investigated in dry AMD. The approaches ...[more]