Recurrence and Mortality Risk of Merkel Cell Carcinoma by Cancer Stage and Time From Diagnosis.

ABSTRACT:

Importance

Merkel cell carcinoma (MCC) often behaves aggressively; however, disease-recurrence data are not captured in national databases, and it is unclear what proportion of patients with MCC experience a recurrence (estimates vary from 27%-77%). Stage-specific recurrence data that includes time from diagnosis would provide more precise prognostic information and contribute to risk-appropriate clinical surveillance.

Objective

To estimate risk of stage-specific MCC recurrence and mortality over time since diagnosis.

Design, setting, and participants

This prospective cohort study included 618 patients with MCC who were prospectively enrolled in a Seattle-based data repository between 2003 and 2019. Of these patients, 223 experienced a recurrence of MCC. Data analysis

SUBMITTER: McEvoy AM 

PROVIDER: S-EPMC8867389 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature