Evaluation of the Antibacterial and Anti-Inflammatory Effects of a Natural Products-Containing Toothpaste.

ABSTRACT: Fluoride-containing toothpaste is daily used in toothbrush. Some compounds derived from natural herbs that have antibacterial and anti-inflammatory activities has attracted increasing attention as potential supplements for the control of oral diseases. In this paper, a natural product mixture (NPM-8) containing eight herbs extracts was added to toothpaste, and its antibacterial and anti-inflammatory effects were investigated. The results showed that NPM-8-containing toothpaste exhibited superior and faster inhibitory and bactericidal effects against S. mutans, S. sanguinis and P. gingivalis than that of the NPM-8-free toothpaste. NPM-8-containing toothpaste significantly reduced the biomass of single-species or three-species biofilms. The cytotoxicity of the NPM-8-cont

SUBMITTER: Qi C 

PROVIDER: S-EPMC8867695 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature