Pathogens and Antibiotic Susceptibilities of Global Bacterial Keratitis: A Meta-Analysis.

ABSTRACT: Bacterial keratitis (BK) is the most common type of infectious keratitis. The spectrum of pathogenic bacteria and their susceptibility to antibiotics varied with the different regions. A meta-analysis was conducted to review the global culture rate, distribution, current trends, and drug susceptibility of isolates from BK over the past 20 years (2000-2020). Four databases were searched, and published date was limited between 2000 and 2020. Main key words were "bacterial keratitis", "culture results" and "drug resistance". Forty-two studies from twenty-one countries (35 cities) were included for meta-analysis. The overall positive culture rate was 47% (95%CI, 42-52%). Gram-positive cocci were the major type of bacteria (62%), followed by Gram-negative bacilli (30%), Gram-positive bacilli (5

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC8868051 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature