Role of blood pressure on stroke-related mortality: a 45-year follow-up study in China.

ABSTRACT:

Background

Hypertension is associated with stroke-related mortality. However, the long-term association of blood pressure (BP) and the risk of stroke-related mortality and the influence path of BP on stroke-related death remain unknown. The current study aimed to estimate the long-term causal associations between BP and stroke-related mortality and the potential mediating and moderated mediating model of the associations.

Methods

This is a 45-year follow-up cohort study and a total of 1696 subjects were enrolled in 1976 and 1081 participants died by the latest follow-up in 2020. COX proportional hazard model was used to explore the associations of stroke-related death with baseline systolic blood pressure (SBP)/diastolic blood pressure (DBP) categories and BP changes from 19

SUBMITTER: Wang S 

PROVIDER: S-EPMC8869560 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature