Alterations of the Gut Microbiome Associated to Methane Metabolism in Mexican Children with Obesity.

ABSTRACT: Gut microbiota is associated with the development of metabolic disorders. To study its association with childhood obesity, we performed a cross-sectional study with 46 children (6-12 years old). We collected fecal samples, food-frequency questionnaires (FFQs), and anthropometric measurements. Shotgun metagenomics were used to obtain the microbial taxonomic diversity and metabolic potential. We identified two dietary profiles characterized by complex carbohydrates and proteins (pattern 1) and saturated fat and simple carbohydrates (pattern 2). We classified each participant into normal weight (NW) or overweight and obese (OWOB) using their body mass index (BMI) z-score. The ratio of Firmicutes/Bacteroidetes and alpha diversity were not different between the BMI groups. Genera contributing t

SUBMITTER: Murga-Garrido SM 

PROVIDER: S-EPMC8870140 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature