Early Auditory Processing Predicts Efficient Working Memory Functioning in Schizophrenia.

ABSTRACT: Early auditory processing (EAP) deficits have been consistently documented in individuals diagnosed with schizophrenia (SZ). However, a relationship between EAP and executive attention has not been confirmed in SZ versus healthy controls (HC). The current study aimed to demonstrate that unlike HC, in SZ patients, auditory change-detection event-related potentials (ERPs) are significantly associated with executive working memory (WM) functioning. Additionally, correlational analyses investigated the relationships between patients' auditory ERPs, WM performance, and schizophrenia symptom severity scores. We examined verbal WM accuracy associated with "executive-control" prefrontal cortex mechanisms and EAP ERPs under midline prefrontal electrodes in 12 SZ patients versus 12 demographically m

SUBMITTER: Meiron O 

PROVIDER: S-EPMC8870168 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature