Recent Developments of Circulating Tumor Cell Analysis for Monitoring Cutaneous Melanoma Patients.

ABSTRACT: Circulating tumor cells (CTCs) have been studied using multiple technical approaches for interrogating various cancers, as they allow for the real-time assessment of tumor progression, disease recurrence, treatment response, and tumor molecular profiling without the need for a tumor tissue biopsy. Here, we will review studies from the last 15 years on the assessment of CTCs in cutaneous melanoma patients in relation to different clinical outcomes. The focus will be on CTC detection in blood samples obtained from cutaneous melanoma patients of different clinical stages and treatments utilizing multiple platforms. Assessment of multiple molecular melanoma-associated antigen (MAA) markers by quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) was the most common assay allowi

SUBMITTER: Shoji Y 

PROVIDER: S-EPMC8870206 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature